Bitcoin, along with other cryptocurrencies, has been described as an economic bubble by at least eight Nobel Memorial Prize in Economic Sciences laureates, including Robert Shiller,[193] Joseph Stiglitz,[194] and Richard Thaler.[195][14] Noted Keyensian economist Paul Krugman wrote in his New York Times column criticizing bitcoin, calling it a bubble and a fraud;[196] and professor Nouriel Roubini of New York University called bitcoin the "mother of all bubbles."[197] Central bankers, including former Federal Reserve Chairman Alan Greenspan,[198] investors such as Warren Buffett,[199][200] and George Soros[201] have stated similar views, as have business executives such as Jamie Dimon and Jack Ma.[202]

In Ethereum all smart contracts are stored publicly on every node of the blockchain, which has costs.[57] Being a blockchain means it is secure by design and is an example of a distributed computing system with high Byzantine fault tolerance. The downside is that performance issues arise in that every node is calculating all the smart contracts in real time, resulting in lower speeds.[57] As of January 2016, the Ethereum protocol could process about 25 transactions per second.[57] In comparison, the Visa payment platform processes 45,000 payments per second leading some to question the scalability of Ethereum.[58] On 19 December 2016, Ethereum exceeded one million transactions in a single day for the first time.[59]

The overwhelming majority of bitcoin transactions take place on a cryptocurrency exchange, rather than being used in transactions with merchants.[138] Delays processing payments through the blockchain of about ten minutes make bitcoin use very difficult in a retail setting. Prices are not usually quoted in units of bitcoin and many trades involve one, or sometimes two, conversions into conventional currencies.[32] Merchants that do accept bitcoin payments may use payment service providers to perform the conversions.[139]
Researchers have pointed out at a "trend towards centralization". Although bitcoin can be sent directly from user to user, in practice intermediaries are widely used.[32]:220–222 Bitcoin miners join large mining pools to minimize the variance of their income.[32]:215, 219–222[115]:3[116] Because transactions on the network are confirmed by miners, decentralization of the network requires that no single miner or mining pool obtains 51% of the hashing power, which would allow them to double-spend coins, prevent certain transactions from being verified and prevent other miners from earning income.[117] As of 2013 just six mining pools controlled 75% of overall bitcoin hashing power.[117] In 2014 mining pool obtained 51% hashing power which raised significant controversies about the safety of the network. The pool has voluntarily capped their hashing power at 39.99% and requested other pools to act responsibly for the benefit of the whole network.[118] Between 2017 and 2019 over 70% of the hashing power and 90% of transactions were operating from China.[119]